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One out of every 10 men is suffering impotence & erectile dysfunctions. While we blame it to stress, lifestyle & wrong dietary choices which by the way is true, our complex biochemistry points this vascular dysfunction ( yes this is vascular dysfunction, read on to know) to functional loss of nitric oxide production. It is no brainer that endothelium lines every single blood vessel inside our body including sexual organs. One of the major functions of nitric oxide is regulating blood flow & vasodilation of blood vessels. If there is no nitric oxide, there is no vasodilation of blood vessels of sex organs, there is no engorgement & erection of penis, causing erectile dysfunction If we understand this really complex biochemistry, erectile dysfunction is early warning sign of range of chronic & systemic diseases If you have endothelial dysfunction in cells of sex organs, the conditions which caused that will also cause endothelial dysfunction in coronary arteries, in heart, liver, kidney, brain & every original in the body Loss of nitric oxide production is a function of endothelial dysfunction caused by inflammation( gut microbiome comes into picture), oxidative stress, immune dysfunction as well as oral dysbiosis which disrupts nitrate-nitrite pathway (via oral microbiome) If you think new age sexual wellness products or Phosphodiesterase inhibitors such as viagra could help, it would surprise you that these drugs or products do not work in 50% of men as they are not nitric oxide donors but depend upon nitric oxide to do its job. So if your body is not producing NO( substrates for viagra) which activates second messenger -cyclic GMP which vasodilates blood vessels, viagra will not help. Some of the pertinent risk factors which could shut down nitric oxide production include use of mouthwash, fluoride in toothpaste, antacids, consumption of bad fats such as processed vegetable or seed oils & chronic inflammation & oxidative stress caused by oral or gut microbial dysbiosis. In order to fix your sexual health issues, restore your nitric oxide production rather than shelling out money on these non effective drugs or wellness supplements. We at Genefitletics, analyse functions of your gut & oral microbiome to understand the root cause of inflammation, oxidative stress & disruption of nitric oxide production & restore your biological functions by personalising nutrition as medicine. More details here: www.genefitletics.com

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